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OSTEOSYS CO LTD small animal dxa scanner osteosys insight
GSK3β phosphorylation and content in femur samples obtained from male RR9 mice (A and B) Bone mineral content (BMC) and bone mineral density (BMD) of the individual bones obtained from a small <t>animal</t> <t>DXA</t> scanner. (C) Representative western blot images of phosphorylated (Ser9) and total GSK3β. (D and E) Western blot analysis of phosphorylated (Ser9) and total GSK3β content normalized to ponceau. (F) GSK3 activation status measured as the ratio of phosphorylated (Ser9) GSK3β relative to total GSK3β. (G) Representative DXA scan showing region-specific analysis of the femur, tibia, and lumbar spine in mice. (H) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured at baseline. (I) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (J) Western blot analysis of soleus muscle FNDC5 from GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (K) Proposed tissue crosstalk between muscle and bone with muscle-specific Gsk3 deletion leading to an increase in FNDC5 and tibia BMD. ∗p < 0.05, ∗∗∗p < 0.001 using a Student’s t test (n = 6–12 per group for (A–F); n = 3–5 per group for (H–J). For (A–F), GC and VIV controls were combined to increase statistical power. All values are presented as means ± SEM.
Small Animal Dxa Scanner Osteosys Insight, supplied by OSTEOSYS CO LTD, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target"

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target

Journal: iScience

doi: 10.1016/j.isci.2023.107047

GSK3β phosphorylation and content in femur samples obtained from male RR9 mice (A and B) Bone mineral content (BMC) and bone mineral density (BMD) of the individual bones obtained from a small animal DXA scanner. (C) Representative western blot images of phosphorylated (Ser9) and total GSK3β. (D and E) Western blot analysis of phosphorylated (Ser9) and total GSK3β content normalized to ponceau. (F) GSK3 activation status measured as the ratio of phosphorylated (Ser9) GSK3β relative to total GSK3β. (G) Representative DXA scan showing region-specific analysis of the femur, tibia, and lumbar spine in mice. (H) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured at baseline. (I) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (J) Western blot analysis of soleus muscle FNDC5 from GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (K) Proposed tissue crosstalk between muscle and bone with muscle-specific Gsk3 deletion leading to an increase in FNDC5 and tibia BMD. ∗p < 0.05, ∗∗∗p < 0.001 using a Student’s t test (n = 6–12 per group for (A–F); n = 3–5 per group for (H–J). For (A–F), GC and VIV controls were combined to increase statistical power. All values are presented as means ± SEM.
Figure Legend Snippet: GSK3β phosphorylation and content in femur samples obtained from male RR9 mice (A and B) Bone mineral content (BMC) and bone mineral density (BMD) of the individual bones obtained from a small animal DXA scanner. (C) Representative western blot images of phosphorylated (Ser9) and total GSK3β. (D and E) Western blot analysis of phosphorylated (Ser9) and total GSK3β content normalized to ponceau. (F) GSK3 activation status measured as the ratio of phosphorylated (Ser9) GSK3β relative to total GSK3β. (G) Representative DXA scan showing region-specific analysis of the femur, tibia, and lumbar spine in mice. (H) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured at baseline. (I) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (J) Western blot analysis of soleus muscle FNDC5 from GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (K) Proposed tissue crosstalk between muscle and bone with muscle-specific Gsk3 deletion leading to an increase in FNDC5 and tibia BMD. ∗p < 0.05, ∗∗∗p < 0.001 using a Student’s t test (n = 6–12 per group for (A–F); n = 3–5 per group for (H–J). For (A–F), GC and VIV controls were combined to increase statistical power. All values are presented as means ± SEM.

Techniques Used: Phospho-proteomics, Western Blot, Activation Assay


Figure Legend Snippet:

Techniques Used: Software

Related Articles

Phospho-proteomics:

Article Title: The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to measure body composition in anesthetized mice (vapourized isoflurane, 5% in O2) prior to the start of the diet intervention and at 11 weeks into the diet.

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to scan the individual femur bones collected from the RR9 mission.

Article Title: Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca 2+ ATPase uncoupling in muscle
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT; Scintica) was used to noninvasively measure body composition in anesthetized mice (vaporized isoflurane 5% in O 2 ) at 4 and 6 weeks into the lithium treatment.

Western Blot:

Article Title: The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to measure body composition in anesthetized mice (vapourized isoflurane, 5% in O2) prior to the start of the diet intervention and at 11 weeks into the diet.

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to scan the individual femur bones collected from the RR9 mission.

Article Title: Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca 2+ ATPase uncoupling in muscle
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT; Scintica) was used to noninvasively measure body composition in anesthetized mice (vaporized isoflurane 5% in O 2 ) at 4 and 6 weeks into the lithium treatment.

Activation Assay:

Article Title: The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to measure body composition in anesthetized mice (vapourized isoflurane, 5% in O2) prior to the start of the diet intervention and at 11 weeks into the diet.

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to scan the individual femur bones collected from the RR9 mission.

Article Title: Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca 2+ ATPase uncoupling in muscle
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT; Scintica) was used to noninvasively measure body composition in anesthetized mice (vaporized isoflurane 5% in O 2 ) at 4 and 6 weeks into the lithium treatment.

Software:

Article Title: The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to measure body composition in anesthetized mice (vapourized isoflurane, 5% in O2) prior to the start of the diet intervention and at 11 weeks into the diet.

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to scan the individual femur bones collected from the RR9 mission.

Article Title: Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca 2+ ATPase uncoupling in muscle
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT; Scintica) was used to noninvasively measure body composition in anesthetized mice (vaporized isoflurane 5% in O 2 ) at 4 and 6 weeks into the lithium treatment.

Control:

Article Title: The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to measure body composition in anesthetized mice (vapourized isoflurane, 5% in O2) prior to the start of the diet intervention and at 11 weeks into the diet.

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to scan the individual femur bones collected from the RR9 mission.

Article Title: Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca 2+ ATPase uncoupling in muscle
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT; Scintica) was used to noninvasively measure body composition in anesthetized mice (vaporized isoflurane 5% in O 2 ) at 4 and 6 weeks into the lithium treatment.

Activity Assay:

Article Title: The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to measure body composition in anesthetized mice (vapourized isoflurane, 5% in O2) prior to the start of the diet intervention and at 11 weeks into the diet.

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to scan the individual femur bones collected from the RR9 mission.

Article Title: Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca 2+ ATPase uncoupling in muscle
Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT; Scintica) was used to noninvasively measure body composition in anesthetized mice (vaporized isoflurane 5% in O 2 ) at 4 and 6 weeks into the lithium treatment.



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OSTEOSYS CO LTD small animal dxa scanner osteosys insight
GSK3β phosphorylation and content in femur samples obtained from male RR9 mice (A and B) Bone mineral content (BMC) and bone mineral density (BMD) of the individual bones obtained from a small <t>animal</t> <t>DXA</t> scanner. (C) Representative western blot images of phosphorylated (Ser9) and total GSK3β. (D and E) Western blot analysis of phosphorylated (Ser9) and total GSK3β content normalized to ponceau. (F) GSK3 activation status measured as the ratio of phosphorylated (Ser9) GSK3β relative to total GSK3β. (G) Representative DXA scan showing region-specific analysis of the femur, tibia, and lumbar spine in mice. (H) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured at baseline. (I) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (J) Western blot analysis of soleus muscle FNDC5 from GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (K) Proposed tissue crosstalk between muscle and bone with muscle-specific Gsk3 deletion leading to an increase in FNDC5 and tibia BMD. ∗p < 0.05, ∗∗∗p < 0.001 using a Student’s t test (n = 6–12 per group for (A–F); n = 3–5 per group for (H–J). For (A–F), GC and VIV controls were combined to increase statistical power. All values are presented as means ± SEM.
Small Animal Dxa Scanner Osteosys Insight, supplied by OSTEOSYS CO LTD, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/small+animal+dxa+scanner+osteosys+insight/small+animal+dxa+scanner+osteosys+insight/pmc10285634-230-1-5
Average 90 stars, based on 1 article reviews
small animal dxa scanner osteosys insight - by Bioz Stars, 2026-11
90/100 stars
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GSK3β phosphorylation and content in femur samples obtained from male RR9 mice (A and B) Bone mineral content (BMC) and bone mineral density (BMD) of the individual bones obtained from a small animal DXA scanner. (C) Representative western blot images of phosphorylated (Ser9) and total GSK3β. (D and E) Western blot analysis of phosphorylated (Ser9) and total GSK3β content normalized to ponceau. (F) GSK3 activation status measured as the ratio of phosphorylated (Ser9) GSK3β relative to total GSK3β. (G) Representative DXA scan showing region-specific analysis of the femur, tibia, and lumbar spine in mice. (H) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured at baseline. (I) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (J) Western blot analysis of soleus muscle FNDC5 from GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (K) Proposed tissue crosstalk between muscle and bone with muscle-specific Gsk3 deletion leading to an increase in FNDC5 and tibia BMD. ∗p < 0.05, ∗∗∗p < 0.001 using a Student’s t test (n = 6–12 per group for (A–F); n = 3–5 per group for (H–J). For (A–F), GC and VIV controls were combined to increase statistical power. All values are presented as means ± SEM.

Journal: iScience

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target

doi: 10.1016/j.isci.2023.107047

Figure Lengend Snippet: GSK3β phosphorylation and content in femur samples obtained from male RR9 mice (A and B) Bone mineral content (BMC) and bone mineral density (BMD) of the individual bones obtained from a small animal DXA scanner. (C) Representative western blot images of phosphorylated (Ser9) and total GSK3β. (D and E) Western blot analysis of phosphorylated (Ser9) and total GSK3β content normalized to ponceau. (F) GSK3 activation status measured as the ratio of phosphorylated (Ser9) GSK3β relative to total GSK3β. (G) Representative DXA scan showing region-specific analysis of the femur, tibia, and lumbar spine in mice. (H) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured at baseline. (I) Region-specific BMD analysis in mobile GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (J) Western blot analysis of soleus muscle FNDC5 from GSK3 mKD and GSK3 flox mice measured after 7 days of HLS. (K) Proposed tissue crosstalk between muscle and bone with muscle-specific Gsk3 deletion leading to an increase in FNDC5 and tibia BMD. ∗p < 0.05, ∗∗∗p < 0.001 using a Student’s t test (n = 6–12 per group for (A–F); n = 3–5 per group for (H–J). For (A–F), GC and VIV controls were combined to increase statistical power. All values are presented as means ± SEM.

Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to scan the individual femur bones collected from the RR9 mission.

Techniques: Phospho-proteomics, Western Blot, Activation Assay

Journal: iScience

Article Title: Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target

doi: 10.1016/j.isci.2023.107047

Figure Lengend Snippet:

Article Snippet: A small animal DXA scanner (OsteoSys InSIGHT, Scintica) was used to scan the individual femur bones collected from the RR9 mission.

Techniques: Software